Malawi stable DMP dimethyl phthalate DMP for pvc

Malawi stable DMP dimethyl phthalate DMP for pvc

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Malawi stable DMP dimethyl phthalate DMP for pvc

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Malawi stable DMP dimethyl phthalate DMP for pvc

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Malawi stable DMP dimethyl phthalate DMP for pvc

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Malawi stable DMP dimethyl phthalate DMP for pvc

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Malawi stable DMP dimethyl phthalate DMP for pvc
  • What is dimethyl phthalate (DMP)?
  • Dimethyl phthalate (DMP) is a member of the group of esters of phthalic acid commonly known as phthalates, used ubiquitously as solvents and plasticisers worldwide. The Phthalate Esters Panel of the American Chemistry Council (2006 revised) derived three categories of phthalates based on use, physicochemical and toxicological properties.
  • Is DMP a LMW phthalate?
  • The NICNAS Phthalates Hazard Compendium (NICNAS 2008b) contains a comparative analysis of toxicity endpoints across 24 ortho-phthalates, including DMP. DMP has a straight carbon chain length of ≤3 and therefore is considered a LMW phthalate (refer to Section 2 for definition).
  • Is DMP a substitute for DINP?
  • DMP is a LMW phthalate and thus it is not likely to substitute for DINP—a HMW phthalate commonly used in PVC toys and childcare articles. In the absence of DMP use data in the two scenarios considered, assumptions may need to be made.
  • Is DMP used in cosmetic and personal care products in Australia?
  • While it is known that DMP is used in cosmetic and personal care products in Australia, information on the DMP levels in these products is insufficient. Accordingly, the exposure estimate is based on the usage and concentration of an alternative phthalate, in this case DEP, which is commonly reported in cosmetic products in Australia.
  • What is the bioavailability of DMP?
  • DMP is rapidly and almost completely absorbed following oral administration. The bioavailability via the oral route is assessed as 100 % for both adults and children. Bioavailability via dermal absorption is not likely to exceed 10 % in humans.
  • What is the concentration of DMP in household products?
  • Concentrations of DMP in domestic detergents, cosmetics, perfumes and personal care products are highly variable and range from 0.00004 % to 34 % (in combination with its analogue diethyl phthalate (DEP)).