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- Is dimethyl phthalate soluble in water?
- Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). ?) Dimethyl phthalate (DMP) is an organic compound and phthalate ester. it is a colourless and oily liquid that is soluble in organic solvents, but which is only poorly soluble in water (~4 g/L).
- What is dimethyl phthalate used for?
- Dimethyl phthalate is able to dissolve nitrocellulose which made it historically important in some automotive coatings and vanishes. DMP can be used as an insect repellent and is especially useful against ixodid ticks responsible for Lyme disease.
- Is dimethyl phthalate carcinogenic?
- The U.S Environmental Protection Agency has classified Dimethyl phthalate as not classifiable for human carcinogenicity. Its oral LD50 is 4390 to 8200 mg/kg bw/d in rats and the dermal LD50 is 38000 mg/kg bw in rats and more than 4800 mg/kg bw in guinea pigs.
- How much monomethyl phthalate (DMP) is toxicity?
- After an orally administered dose of 0.1mL of DMP, about 77% of monomethyl phthalate and 8% of DMP have been detected in urine collected for 24 hours from male rats. Acute oral toxicity results in an LD50 of 8,2, 5,2, 2,9, 10,1 and 8,6 mg/kg for rats, rabbits, guinea pigs, chicks, and mice respectively.
- How is dimethyl phthalate made?
- Dimethyl phthalate is manufactured commercially via the esterification of phthalic anhydride with methanol. The reaction can be catalysed by a strong acid, such as sulfuric acid; various lewis acids may be used as an alterative, including complexes of titanium, zirconium or tin.
- Can DMP be absorbed in rats?
- Studies have shown that DMP is readily absorbed in the gastrointestinal tract of rats. After an orally administered dose of 0.1mL of DMP, about 77% of monomethyl phthalate and 8% of DMP have been detected in urine collected for 24 hours from male rats.
