cost-effective acetyl tributyl citrate ATBC in Congo

cost-effective acetyl tributyl citrate ATBC in Congo

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cost-effective acetyl tributyl citrate ATBC in Congo

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cost-effective acetyl tributyl citrate ATBC in Congo

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cost-effective acetyl tributyl citrate ATBC in Congo

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cost-effective acetyl tributyl citrate ATBC in Congo

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cost-effective acetyl tributyl citrate ATBC in Congo
  • What is tributyl 2-acetylcitrate?
  • Tributyl 2-acetylcitrate is a hydrophobic biodegradable plasticizer, that is usually synthesized by esterification of citric acid. Pharmaceutically, it is used as an excipient, which is generally applied as a thin film over the tablets or capsules.
  • Does electron beam radiation affect the migration behavior of acetyl tributyl citrate?
  • Study of the migration behavior of acetyl tributyl citrate from PVDC/PVC film into fish fillets as affected by intermediate doses of electron beam radiation The first three authors contributed equally to this paper. Recommended articles cannot be displayed at this time.
  • Does ATBC stably interact with target genes?
  • To substantiate our analytical findings, we conducted a molecular docking study, which unveiled a pronounced affinity between ATBC and the five core target genes—AR, HDAC1, CREBBP, STAT3, and PARP1.This discovery suggests that ATBC has the capacity to spontaneously and stably interact with these target genes.
  • Does ATBC pose a clinical risk?
  • Current literature does not clearly indicate that ATBC presents a clinical risk. However, as a plasticizer extensively utilized in daily life, ATBC may still present several potential risks due to prolonged and significant human exposure.
  • How does ATBC affect bone metabolism?
  • Moreover, ATBC’s influence transcends the thyroid hormone signaling axis, as it may indirectly modulate bone metabolism through a vast array of intricate signaling cascades, including insulin, adipocytokine, AMPK, FoxO, glucagon, and Notch pathways.
  • Is ATBC toxic?
  • ATBC, a colorless, odorless, lipophilic liquid with low water solubility, has been deemed relatively non-toxic in animal studies. However, its widespread use in PVC arteriovenous catheters in cardiac surgery poses a significant concern, as blood, a lipid-rich medium, can readily dissolve and absorb ATBC (Zygoura et al., 2011).