chemical plasticizer dimethyl phthalate in Ukraine

chemical plasticizer dimethyl phthalate in Ukraine

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chemical plasticizer dimethyl phthalate in Ukraine

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chemical plasticizer dimethyl phthalate in Ukraine

hot sale dimethyl phthalate plasticizers

chemical plasticizer dimethyl phthalate in Ukraine

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chemical plasticizer dimethyl phthalate in Ukraine

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chemical plasticizer dimethyl phthalate in Ukraine
  • How much monomethyl phthalate (DMP) is toxicity?
  • After an orally administered dose of 0.1mL of DMP, about 77% of monomethyl phthalate and 8% of DMP have been detected in urine collected for 24 hours from male rats. Acute oral toxicity results in an LD50 of 8,2, 5,2, 2,9, 10,1 and 8,6 mg/kg for rats, rabbits, guinea pigs, chicks, and mice respectively.
  • Is dimethyl phthalate carcinogenic?
  • The U.S Environmental Protection Agency has classified Dimethyl phthalate as not classifiable for human carcinogenicity. Its oral LD50 is 4390 to 8200 mg/kg bw/d in rats and the dermal LD50 is 38000 mg/kg bw in rats and more than 4800 mg/kg bw in guinea pigs.
  • How is dimethyl phthalate made?
  • Dimethyl phthalate is manufactured commercially via the esterification of phthalic anhydride with methanol. The reaction can be catalysed by a strong acid, such as sulfuric acid; various lewis acids may be used as an alterative, including complexes of titanium, zirconium or tin.
  • What is dimethyl phthalate used for?
  • Dimethyl phthalate is able to dissolve nitrocellulose which made it historically important in some automotive coatings and vanishes. DMP can be used as an insect repellent and is especially useful against ixodid ticks responsible for Lyme disease.
  • Is dimethyl phthalate a potent male rat reproductive tract toxicant?
  • The results provide supportive evidence that gestational exposure to dimethyl phthalate isnot a potent male rat reproductive tract toxicant like other phthalate esters, such as DBP and DEHP.
  • How has phthalate production changed over the past 5 years?
  • Recently, production hasdeclined slightly from 4,000 metric tons (2005) to 3,600 metric tons (2008). DMP’s proportion of the total phthalate production market has remained static at approximately 0.6-0.7% over the past 5 years (Bizzari, 2007, 2009).